
Diagram Explained
After a bite from an infected female anopheline mosquito, the malarial sporozoites travel through the bloodstream to the liver. Once in the liver they mature and release their next form merzoites which enter back into the blood stream and infect red blood cells of all kinds.
Then when the merozoite is inside the red blood cells the merozoites multiply causing the red blood cell to burst within 48-72 hours. The organisms that burst from the red blood cell are the newly formed parasitic trophozoite cells which attack other red blood cells. (Malariaburdenandinterventions) The trophozoites then mature into gametocytes that infect mosquitos whenever they drink from an infected human, from these gametocytes a non infected mosquito can become infected and spread it to its future hosts. The trophozoites can also attack another red blood cell repeating the infectious process.